The Stem Cell Podcast

The Stem Cell Podcast

A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

  1. Jul 7

    Ep. 324: “From Stem Cells to Living Tissues” Featuring Drs. Yifei Miao and Anca Pasca

    Guest: This special episode, created in partnership with the ISSCR Early Career Advisory Committee, features two rising leaders in stem cell research. Dr. Yifei (Simon) Miao, a Professor at the Chinese Academy of Sciences, discusses engineering vascularized organoids and integrating bioengineering approaches to build more physiologically relevant human tissues. Dr. Anca Pașca, an Assistant Professor at Stanford Medicine, explores how stem cell-derived brain organoids and assembloids are advancing our understanding of neonatal brain injury and neurodevelopmental disorders, with the goal of developing new therapies for vulnerable infants. If you’d like to nominate yourself or a colleague for our Early Career Researcher Series, submit your nomination here. Featured Products and Resources: Join us at ISSCR 2026 to discover breakthroughs, technologies, and clinical insights you can take back to your lab. Enter to win 350 US dollars or equivalent toward refreshments to fuel your journal club discussions. The Stem Cell Science Round Up Editing Early Human Development – Base editing of human embryos reveals that NANOG is essential for epiblast formation and human pluripotency. Reprogramming Colorectal Cancer – Loss of GATA6 promotes colorectal cancer liver metastasis by driving multilineage cellular plasticity. Precision Medicine for Pancreatitis – Patient-derived organoids identify chronic pancreatitis subtypes and reveal CFTR modulators as a potential treatment. Tracking Heart Organoids – A wireless cantilever platform enables high-throughput measurement of contractile forces in human cardiac organoids. Photo Reference: Courtesy of Drs. Yifei (Simon) Miao and Anca Pasca Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  2. Jun 23

    Ep. 323: “Building the Blastema” Featuring Dr. Mekayla Storer

    Guest: Dr. Mekayla Storer is an Associate Professor at the University of Cambridge and a Principal Investigator at the Cambridge Stem Cell Institute. She discusses how mammalian digit tips regenerate after injury, focusing on the formation of the blastema and the cellular and molecular mechanisms that distinguish regeneration from scarring. She highlights the role of the extracellular matrix, tissue mechanics, and regenerative microenvironments in directing tissue repair, and explores how insights from digit tip regeneration may inform strategies to promote regeneration in other organs. Featured Products and Resources: Join us at ISSCR and discover breakthroughs, technologies, and clinical insights you can take back to your lab. Kick start your own journal club using our free toolkit equipped with downloadable checklists and templates. The Stem Cell Science Round Up Modeling EMT in Human Cells – Scientists have developed a human iPSC-based platform that enables standardized, multimodal analysis of epithelial-to-mesenchymal transition dynamics across 2D and 3D contexts. Modeling Persistent Ebola Infection – Human brain organoids reveal how persistent Ebola virus infection in neural cells drives long-term inflammation and viral evolution. Reducing Retinal Graft Rejection – Transient JAK inhibition reduces immune rejection of stem cell-derived retinal grafts and improves visual recovery. Enhancing Renal Regeneration – Targeting ENPP1 with a therapeutic antibody enhances regeneration and restores function after acute kidney injury. Photo Reference: Courtesy of Dr. Mekayla Storer Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

  3. Jun 9

    Ep. 322: “Healing Hearts with Macrophages” Featuring Dr. Filipa Simões

    Guest: Dr. Filipa Simões is a Group Leader at the University of Oxford and Co-Director of the Oxford Organoid Hub. She discusses how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury. Using zebrafish models, stem cell–derived cardiac organoids, and spatial genomics approaches, she explores the molecular signals that govern macrophage identity and function, with the goal of uncovering new strategies to promote cardiac regeneration and limit fibrosis. Featured Products and Resources: Join us at ISSCR and discover the breakthroughs and technologies you can take straight back to your lab. Enter to win 350 US dollars or equivalent towards refreshments to fuel your next journal club. The Stem Cell Science Round Up iPSC Therapy for Heart Failure – Engineered heart muscle grafts derived from iPSCs increased heart wall thickness and improved cardiac function in patients with heart failure. Inflammatory Memory in HSCs – A distinct human HSC subset retains inflammatory memory, influencing blood production, aging, and disease risk. Organoid-Mediated Vision Recovery – Transplanted human retinal organoids partially restored vision after complete optic nerve transection in rats. Improving HSPC Gene Therapy – A new selection strategy enriches precisely edited hematopoietic stem cells while reducing unwanted genomic alterations. Photo Reference: Courtesy of Filipa Simões. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

4.7
out of 5
103 Ratings

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A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

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