Let's Talk Wellness Now

Let's Talk Wellness Now

Deep Health, Real Answers - hosted by Dr. Deb

  1. 1d ago

    Episode 270 – Chronic Symptoms Are a Hidden Message: How to Listen and Finally Heal | Dr. Kelly McCann

    Dr. Deb Muth 00:03What if your diagnosis isn’t actually your diagnosis? What if the fatigue, brain fog, anxiety, and inflammation you’ve been told are normal are actually signals your body is reacting to something in your environment? Something no one ever tested.What if the reason you’re not getting better is because no one is asking the right questions?Today, we’re exposing one of the most overlooked drivers of chronic illness, and why so many people are being dismissed, misdiagnosed, and left without answers.You guys can insert, one of our ads in here, that’d be great.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting-edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective. And today, we’re diving into the hidden drivers of chronic illness through the lens of functional and environmental medicine.If you or someone you love has been diagnosed with a chronic condition or is struggling with unexplained neurological symptoms, like fatigue, brain fog, numbness, or chronic pain. This episode is for you. So, grab your cup of coffee, tea, or whatever helps you unwind.Settle in, and let’s get started on your journey to deeper healing.Today, I’m joined by Dr. Kelly McCann. A board-certified physician in internal medicine and pediatrics, with advanced training in functional, integrative, and environmental medicine. She’s known for her work in mold illness, chronic infections, MCAS, and complex chronic conditions And for helping patients who have been told everything looks normal. She helps them finally get real answers. Dr. Kelly, welcome to the show. I’m so excited to have you here. Share a little bit about what you’re doing these days, and who you are, and who you’re serving with us. Kelly McCann 02:42Thank you. So, my favorite patient population is patients who deal with complex chronic illness, and I didn’t set out to deal with these kinds of patients, but I kept… needing to be able to solve the puzzles, right? So they would come in, and there would be so many things that just didn’t add up and didn’t make sense, and it started with,it started with just doing functional and integrative medicine, and GI issues, and hormone issues, and autoimmune issues, and then it was mold as a driver, and then it was Lyme disease and the other tick-borne infections, and then all of those patients, many of those patients developed mast cell activation syndrome.Which I’ve now gone on and become an expert in, because they all have it.And all the related conditions with MCAS, the Ehlers-Danlos, hypermobility syndrome, POTS, postural orthostatic tachycardic syndrome, and… The one thing that really stuck out to me over the years of treating these patients is the ones who were willing to take a deep look inside. And see how their… their belief patterns, how their thoughts how they perceived themselves, different traumas that they experienced. If they were able to reframe some of the ways that they were thinking about their illness, about themselves, their relationship to themselves, they were the ones who really healed.And not only did they heal physically, they healed emotionally, psychologically, and spiritually. I have some patients who started out disabled, and now are running their own companies. One who, again, same thing, terribly disabled, lots of emotional issues, lots of ups and downs, food sensitivities, oxalate issues, and now she’s a medical intuitive. And she’s just doing fabulously, and has blossomed, right? So, this is a missing piece that we’re not really talking about. Dr. Deb Muth 05:04Yeah, I so agree with you. I see the same thing in my practice, and I treat a lot of the same people you do, and you are so right. Like, if we can get down to a deeper level with them, and address the trauma that happened.And it may be a trauma they never even remembered, right? It could be something that’s just seated in their cells and they don’t remember it. And you don’t directly think it’s causing the illness, but it is getting in the way of them healing. If you can address those things, those are the people that tend to do so much better, I think, versus the people who are getting some mileage out of their illness. That there’s a reason they stay stuck, there’s a reason they stay sick, they’re getting something from it, even though they don’t realize it in the moment.So let’s talk a little bit, before we hopped on the recording, you and I were talking about body, emotion, spirit. A little different than what we’re used to hearing with mind, body, spirit. Talk about your philosophy on this. Kelly McCann 06:01So what I’ve really come to realize is that the mind is getting in the way. And we have this perception that our mind is who we are. Right? We really think that who I am are the thoughts that I have every day. That’s me. And when I’m not getting better, it’s because my body is not… Falling in line with what my mind and my will want to do. So we set up this adversarial relationship. And this has been the philosophy in Western culture since Descartes said, I think therefore I am. Where the mind is supreme, and it is the all-knowing, and the body is just a vehicle for the mind. And every… Therapeutic intervention, from trauma-informed therapy, from, you know, wonderful people who have committed a lot of help and given great information. Bessel van der Kolk, The Body Keeps the Score, Gabor Mate, you know, all of these folks who have done such great work in us understanding trauma I think… The next phase is really recognizing that the body is actually not against us. It is not our enemy. In fact, it is… The body that is speaking to us as the voice piece of our souls and our spirits, that is saying to us, hey. you’re not listening. The path that you are walking down and the way that you are being in the world is not really working for you. It’s not who you are. It’s not who you’re supposed to be on the planet. And we’re trying to get your attention, right? Dr. Deb Muth 07:59Yeah. Kelly McCann 07:59I mean… Dr. Deb Muth 08:00this thing, so I’m gonna talk louder. Kelly McCann 08:02Exactly, exactly! It’s like a little toddler who only can speak in so many words, right? There’s only so many ways that a younger version of ourselves, or our bodies, like, how do our bodies communicate to us? Symptoms and sensations. That’s it. Those are the ways that our bodies communicate. And if we don’t listen to sensations, well, it’s gotta turn it up, it’s gotta turn up the volume, and then we have more symptoms. And then if we’re still like, no, it’s gonna do it my way, it turns up the symptoms some more. And when… We are in this adversarial relationship, we can’t bridge that gap. Can’t bridge that gap, so… What… what happens is thatUnderneath the symptoms and the sensations are emotions. Emotions that have not been processed. Because we’ve been stuffing them down, we believe that they shouldn’t exist, we don’t want to face them, we’re afraid of them, they’re not acceptable, we’re ashamed of them, whatever the reason may be, and they’re stuck in the body. And so the way through is to actually just feel our feelings. Dr. Deb Muth 09:26That’s kind of scary for some people. Kelly McCann 09:28It’s… it’s scary for the… it’s scary for the whole planet! Dr. Deb Muth 09:32For all of this, right? Kelly McCann 09:33For all of us. When we start to feel our feelings, we don’t like it. We’ve been taught it’s not okay. Boys, it’s not okay to cry. Girls, don’t be loud, don’t be angry. You’re a B-I-T-C-H if you do that, right? So there’s so many taboos about feeling our feelings. I have patients who say, I can’t be mad at my father or my mother because I was taught to honor thy father and thy mother. Like, yes, but you’re angry, and guess what?] That ain’t going nowhere until you express it, so… you have a choice. Express it, or hold onto it, and then you just kind of stay here in this space where it’s never expressed. Dr. Deb Muth 10:19Yeah, except in your body, in your physical being, right? Kelly McCann 10:22Except in your physical being. And here’s the magic. Emotions are meant to move through us, right? Emotion. They don’t last for that long!60 to 90 seconds, really? Maybe a couple minutes? Yeah. You really, really feel them. Right? Dr. Deb Muth 10:44Yeah. Kelly McCann 10:46And we’re terrified of that 60 to 90 seconds. Dr. Deb Muth 10:50What might we do to ourselves or to someone in that 60 to 90 seconds, right? I may scream, I may cry, I may not be this person that everybody thinks I’m supposed to be. That person that holds it all together is there for everybody, holds everybody else’s space. So well put together, right? If you’re not that person, then who are you? Are you human? Kelly McCann 11:16Oh, you’re more than human. Yeah, I mean, the way that I would look at it is, I would say, well, you don’t have to put on a show, right? This is really for you. Close the door, lock the… close the windows, get out your pillow. Whatever you need to do. I mean, I have some patients who will write it out. There’s a way to just, like, freeform write, where you don’t actually read it, you just write it out, scribble it out, get it all out on paper, and then burn it, or shred it, or something like that. you can pound a pillow, you can, you know, scream, whatever it is, you can cry. I mean, I think crying is, at least for… for me. Crying is the easiest way to think about it. So, you start crying, you’ve got a few little tears, you know, it’s not too bad, and then it’s a full-on sob, and then at some point, you’re like, okay, I think I need a tissue, right? But it doesn’t last forever

    46 min

  2. Jun 15

    Episode 269 – Peptide Therapy for Women: How BPC-157 & TB-500 Heal Gut, Joints & Inflammation

    Deb 00:00:01Imagine your body has a repair manual, instructions written in your cells that tell tissues how to heal, blood vessels, how to grow, and inflammation when to stop. But what if those instructions got lost somewhere along the way? Well, today I’m talking about peptides, tiny protein fragments that act like biological text messages. Two of them, BPC 157 and TB 500.They’re showing remarkable promise for gut repair, joint recovery, and tissue regeneration. But here’s what nobody’s telling you. Women respond differently to these healing signals, especially during hormonal transitions. And today, we’re uncovering the science behind these regenerative peptides, who actually needs them, and why your doctor might not know about them. Can you guys put our ad right in here and then I’ll go to the standard intro?Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective. And today we’re diving into regenerative peptides BPC157 and TB 500. If you or someone you love is struggling with slow recovery from injury, chronic joint pain, gut inflammation that just won’t quit, or you just feel like your body doesn’t bounce back the way it used to, this episode is for you. Grab a cup of coffee or tea or whatever helps you unwind, settle in, and let’s start you on your journey to deeper healing. We’ll do another sponsor break here. Deb 00:01:52So let’s start with the question I hear constantly in my practice. Dr. Deb, I’m doing everything right. I’m eating clean, I’m exercising, I’m taking my supplements, but I’m still not healing. What am I missing? Well, that answer might surprise you. Sometimes it’s not about what you’re putting in your body. It’s about whether your cells are actually receiving the repair signals they need. That’s where peptides come in. Think of peptides as The body’s original communication system. These short chains of amino acids are like biological post-it notes carrying instructions from one cell to another. They tell your human system when to calm down, your blood vessels when to grow and your tissues when to repair. Now here’s where it gets interesting for women specifically. We know that estrogen plays a massive role in collagen production, vascular health, inflammatory response. When estrogen starts declining, whether that’s perimenopause, postpartum, or even from chronic stress, our natural repair mechanisms slow down dramatically. You might notice it as my joints are aching more, I’m a little more fluid filled, you know, they hurt when I bend them, my injuries take twice as long to heal.Gut issues that suddenly appear out of nowhere and no matter what you do, they don’t seem to repair. Skin has lost its elasticity or just this general sense that your body isn’t keeping up anymore. This is where BPC 157 and TB 500 entered the picture. So BPC 157, short for body protection compound 157, is a naturally occurring peptide sequence found in your gastric juices. And according to a 2024 systemic review published in emerging use of BPC 157 in orthopedic sports medicine, this peptide promotes something called angiogenesis. That’s the formation of new blood vessels and they deliver oxygen and nutrients to damaged tissues. Now TB 500 is a synthetic fragment of thymus and beta-4. Deb 00:04:17A protein your body makes naturally during wound healing and research published in therapeutic peptides in orthopedics in 2025 shows that it works like a cellular first responder rushing to injury sites and coordinating tissue repair through a process called actin regulation. But here’s what makes these peptides different from just taking another supplement. They don’t force your body to do anything.They simply remind yourselves how to heal the way they used to. And for women navigating hormonal changes, autoimmune flares, chronic inflammatory conditions, that distinction matters enormously. all right, let’s get into some of these mechanisms because understanding how something works helps you make informed decisions about whether or not it’s right for you. So,Let’s look at the science. Do these peptides actually work? And if so, how do they work? Let’s start with BPC 157. This works through multiple pathways simultaneously. First, it activates growth factor receptors that stimulate fibroblasts. Those are the cells responsible for making collagen and rebuilding connective tissue. And according to research published in Frontiers and Pharmacology in 2023, titled Regeneration or Risk, BPC 157 also modulates nitric oxide signaling, which enhances vascular repair and reduces oxidative stress at the cellular level. So this is really important because many of us are nitric oxide deficient, especially as we get older, especially since the pandemic, we’re seeing a lot of people being more deficient in nitric oxide and you’re taking nitric oxide, many of you, to help with this process. But if we’re having other issues that don’t allow that nitric oxide to get where it needs to go, that could render it completely useless. So in plain English, when we’re talking about how BPC 157 helps the blood vessels work better and protects your mitochondria, big word for your energy factories and your cells from that inflammatory damage. Deb 00:06:38Now there’s studies in musculoskeletal and gastroenterology models that show BPC157 decreases inflammatory cytokines like TNF-alpha and IL-6. And these are chemical messengers that keep inflammation turned on. So by dialing them down, BPC157 creates an environment where healing can actually happen. Now, where do we know about this?TNFL and IL-6, well, we know it from viruses, we know it from Lyme disease, we know it from mold toxicity. These cytokines are turned up, they’re creating a massive inflammatory response in the body, and you’re struggling to get these things down because of that or potentially other reasons. So here’s where it gets really interesting with women in perimenopause or menopause. When estrogen declines, collagen synthesis slows down. And that’s why we see increased joint pain, slower wound healing, and our changes in the skin’s elasticity during this transition. We see the little wrinkles, the fine lines, we see the subcutaneous fat going away a little bit more. This is partially why this is occurring. And so from research shown in the Journal of Orthopedic Research in 2023 by Leibowitz and colleagues, that they suggest that BPC157 affects on the endothelial layers. So the cells lining the blood vessels and these may mimic some of the estrogen’s protective vascular effects without actually affecting your hormone levels. This is really huge because we know that as women lose estrogen, they have a higher risk for vascular events, heart attack, stroke, things like that. And if people have already had a heart attack or a stroke, We typically recommend that they don’t use estrogen because that could potentiate the risk for another heart attack or a stroke. But that means that you don’t gain the benefits of estrogen either. So if we think about this, we could potentially use BPC 157 to give us some of the benefits that we lost from having estrogen and potentially not being able to use estrogen. And that would be huge for us. Deb 00:08:57And not to mention the reduction of inflammation and the joint pain and the wound healing and the energy and the gut feelings. I mean, there’s just so many benefits to BPC 157 that we could talk about them all day long. But we’ve got to move on. So let’s talk about TB 500. Now this peptide works very differently. Its primary job is promoting cell migration, essentially telling repair cells to go to this spot and what to do when they get there. So it sends a signal, puts a little post-it stamp there and says, Hey, when you get there, fix A, B, C, and D. And there was a study in 2024 in cell biology international that demonstrated that TB 500 increases epithelial closure and improves tendon elasticity in models of repetitive strain injury. So let’s think about that a little bit. What does that really mean?That means faster recovery from exercise induced muscle damage, better healing of overuse injuries like tennis elbow or plantar fasciitis, improved scar tissue remodeling after surgery or a C-section, enhanced recovery from chronic inflammatory conditions affecting soft tissues. And I’ve talked about this several times. I have used these compounds post-surgical personally.And I remember going back to see my surgeon at the two to three week mark for follow-up. And she was amazed at how well everything was healing. And when I asked her if she wanted to know what I was doing, her response was no, but keep doing whatever you’re doing because it’s working. And after three weeks of a major pelvic repair surgery that I had, four hours in surgery, lots of sutures, not comfortable. I was actually walking a mile and didn’t have pain and I was recovering really well and felt amazing. And that is just not typically heard of in surgical procedures like mine. It’s usually a minimum of a six to eight week recovery before you’re starting to do that again. And I give all of the credit to these two peptides. Deb 00:11:17In my clinical practice, I see this play out constantly. Women who train hard, whether that’s CrossFit, running, yoga, or just trying to keep up with active kids, often hit a wall where their recovery can’t keep up pace with their activity level. And TB 500 helps to bridge that gap by optimizing the body’s natural repair timeline. But here’s what I want to emphasize with you. These peptides aren’t magic bullets.They work best when we combine them with proper nutrition and anti-inflammatory diet, adequate sleep, stress management, and we ad

    23 min

  3. Jun 10

    Episode 268 – Mold+Lyme+Genetics: The Root Cause Most Doctors Miss

    Dr. Deb Muth 00:00:09Hi there, how are you? Bob Miller 00:00:10Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28No. Dr. Deb Muth 00:00:29Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35Absolutely. Bob Miller 00:00:36Yeah. Dr. Deb Muth 00:00:37Absolutely. Bob Miller 00:00:36Yeah. Dr. Deb Muth 00:00:37Absolutely. Bob Miller 00:00:38Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48Okay. Dr. Deb Muth 00:00:49And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01No worries. Bob Miller 00:01:16And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33Right? I agree. Bob Miller 00:01:35When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23Oh, nice! Bob Miller 00:02:24And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32Love that. Bob Miller 00:02:34I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44Yeah. Bob Miller 00:02:45And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54Which is so much better. Bob Miller 00:02:56Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03And how much time do we have? Dr. Deb Muth 00:03:04We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16Perfect. Alright. Bob Miller 00:03:18It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23Okay, good. All right, are you all set to get started? Bob Miller 00:03:28I’m good to go, my friend. Dr. Deb Muth 00:03:29I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39Okay, you got it. Dr. Deb Muth 00:03:40Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27Not an option I would want. Bob Miller 00:05:29So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culpritsPrimarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from.Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron.And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’

    1h 22m

  4. Jun 5

    Episode 267 – Environmental Toxins, Nutrition, and Their Role in Chronic Disease Development

    Dr. Deb Muth 00:08What if the toxins in your food and water weren’t just harming our bodies, but rewriting the very code of human health? My guest today, MIT scientist Dr. Stephanie Sineff, has spent over a decade connecting the dots between environmental toxins, metabolic chaos, and neurological decline. You’ll want to hear every word of this conversation. You guys can put our, Serenity ad in here, and then I’ll do the standard intro.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting-edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective.And today, we’re diving into how environmental toxins and nutritional imbalances are silently shaping chronic disease patterns, from autoimmune disorders to neurodegenerative decline. And how we can take back control of our health. So, as usual, grab your cup of coffee, tea, or whatever helps you unwind, settle in, and let’s get started on your journey to deeper healing. So, Dr. Sunif, so glad to have you here. I can’t wait to have this conversation with you. We were just chatting off-camera a few seconds ago about what we’re going to chat about, but tell us a little bit about your background and how you got into this field of looking at toxins and mitochondria. Seneff 01:50Okay, yeah, my background is a bit eclectic, so it starts out with biology. I have an undergraduate degree in biology from MIT. My PhD is in electrical engineering and computer science, so that’s quite a switchover. And most of my career, I was writing computer code to train computers to talk to humans in a natural conversation… conversational interaction with computers. We were pioneers in that space. You can see that it has really taken off now. And actually, by 2006, 2007, I started to realize that the kind of work I did already then was getting compromised by the, by the emergence of AI. And I got concerned that, I wouldn’t be able to sustain the path I was on. And it’s happening now, of course, to the young… many people, young people today, are facing a crisis in computer science, because it used to be if you had skills in hacking code, you were good to go, you know, and that’s just not true anymore, so that’s another whole story, but anyway, I decided I needed to do something different, and I pivoted in a big way in 2007. managed to get the company that had been funding me, a Taiwanese company called Quanta Computers, And they,We’re willing to switch over to funding me to do research on health and toxic chemical exposures. Which was a miracle that they let… they let me switch over to that, and that was fantastic, 2007. So it’s been almost 20 years. that I’ve been looking for toxic chemical exposures and their association with human disease. And I focused initially on autism and heart disease, kind of for personal reasons, because I knew people who had, you know, who had those issues.But it led into a much, much bigger story, and I’m super excited about what’s happened over the last 20 years. It’s been a continual learning experience for me, and I’ve just kept broadening my space in biology, furiously reading papers as I discovered new concepts and trying to explore those. opening up new windows, and it’s just been a profusion of learning over the past 20 years, and I’ve published many papers at this point. Peer-reviewed papers on the topics of toxic chemical exposures and disease. Particularly, glyphosate is the one I really focused on, and I wrote the book, Toxic Legacy, how the weed killer glyphosate is Destroying Our Health and the Environment.That was published in 2021. So. Dr. Deb Muth 04:18So I’m sure you have a few thoughts about the administration wanting to bring that back to be made at home instead of China, right? Seneff 04:26I know, that’s so interesting. And actually, you know, he makes a point that I agree with, which is that we are relying on China. for importing a whole bunch of stuff that’s really toxic, and we’re pouring it all over our food supply, so China’s probably very happy to poison us, you know? Oh, absolutely. It’s kind of ironic that we’re doing that, and he makes a good point that we shouldn’t be relying on China for these chemicals that are poisoning us, but where he misses the point is he says, well, we just need to poison ourselves, you know? Rather than getting rid of that chemical, we need to really change the way we grow food.I think it’s the number one most important thing right now. in America is to change the way we grow food, and it has to be certified organic, regenerative. We need to focus on healing the soil, just as we have to heal the gut. I mean, we’ve really messed up the microbes in both the soil and the gut, and the consequences, as you can see, are a huge problem with human disease. Dr. Deb Muth 05:20They’re devastating. I mean, we have so much chronic illness and so much neurological disease these days, and just the rise of autism, it should be telling us that we’re doing something wrong, right? Seneff 05:31Absolutely. Dr. Deb Muth 05:32We have a problem. For those people who are listening that don’t understand what the term glyphosate is, can you explain that a little bit to them? Seneff 05:39Yeah, so it’s one of the many herbicides that we use. We use herbicides, fungicides, and insecticides in agriculture, all these poisons, and it kind of seems crazy to me that we would think it’s okay to pour poisons all over our food supply. I don’t understand why we think that’s fine.Yeah. You know, categorically. Glyphosate is supposed to be a wonderful chemical, because it’s an herbicide that kills all plants except for those that have been engineered to resist it. And supposedly is completely harmless to humans. And that’s what gets to be, you know, disbelief, because how can something so toxic to plants be harmless to humans? Just, how can it be? Dr. Deb Muth 06:14We haven’t been re-engineered like the seeds that they use from Monsanto, so how can it not affect us if it only affects everything but their seeds that they’ve modified to make grow beautifully under that condition? It doesn’t make any sense. Seneff 06:32Right, and of course, the critical thing they missed is that our gut microbes do have that pathway. It’s the chicken mate pathway that it disrupts. Really critical in all the plants, and in most of the microbes. In the soil and in the gut, and so it kills off the microbes as well as the plants, and when it kills off your gut microbes, you gotta watch out, because gut dysbiosis is a huge thing. And we’ve had so many papers coming out lately that Talking about the relationship between gut dysbiosis and all kinds of different diseases. Dr. Deb Muth 07:01Do you think that’s why we see so much gut dysbiosis these days? Seneff 07:04Oh, absolutely. I think it’s not just glyphosate, because we have lots of poisons that are messing up our gut microbes, but glyphosate is a really big one, because the shikimate pathway is essential for many of the microbes, and they use it to make essential nutrients for the host. So we get compromised as well, just because they can’t make those nutrients in that. Dr. Deb Muth 07:22It’s so… Seneff 07:22lies. Dr. Deb Muth 07:23so much harder today to treat people with gut issues than it was 25 years ago when I started. It was so much easier. And now, it’s, like, nearly impossible sometimes to get some of these people back to a good, healthy gut microbiome, no matter what you do, no matter how well they eat, and all the things that they do. It’s a struggle, for sure, compared to what it was 20 years ago. Seneff 07:44It’s interesting that you have that personal experience, because I think people like you really can see what’s happening. Dr. Deb Muth 07:49and appreciate. Seneff 07:50the difference between then and now. I, of course, as a child, autism was not something I knew about at all. Really, when I was a child. It didn’t exist, basically. I mean, it was so rare. And now, you know, everyone knows someone with autism, you know, pretty much. Dr. Deb Muth 08:08Autism and Parkinson’s and Alzheimer’s seems to be just so much commonplace. Everybody knows somebody in their family that is affected by one of those disorders, if not multiples, and We tend to say it’s genetic, right? Well, there’s got to be a genetic… why wasn’t it genetic 50 years ago, or 100 years ago? But now, all of a sudden, it’s so prevalent in our environment that we’ve just become acceptable of it, and I think that’s wrong for us to do that. We shouldn’t be doing that. Seneff 08:38I know. I find it very interesting how quickly it appears that humans adapt to the new normal, you know? Dr. Deb Muth 08:44Yeah. Seneff 08:45It’s normal that you have, you know. 3% of the kids have autism, that’s normal, you know? It’s just like, no, it’s not. And also, of course, all the Alzheimer’s and dementia and Parkinson’s, as you mentioned, in the elderly, those are connected, because they’re all related to brain problems that are being caused by chemicals that are destroying the brain. Dr. Deb Muth 09:03Yeah. So, how does glyphosphate interact with our body’s ability to absorb those essential nutrients, like sulfur? Seneff 09:12Yeah, well, it’s… that’s a big… that’s a big question. I don’t know where to begin with that one. Glyphosate, you know, it’s a train wreck for the gut microbes, and then that causes the gut dysbiosis. The microbes are unable to produce adequate amounts of nutrients that are essential for the host. And as a consequence, the host cells get sick, you know, so the colonocytes get sick because they’re not getting adequate nutritio

    38 min

  5. May 20

    Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself

    Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Mut

    51 min

  6. May 11

    Episode 263 – Functional and integrative psychiatry: combining nutrition, biochemistry, and lifestyle with mental health care

    Dr. Deb Muth 00:03Welcome to Let’s Talk Wellness Now. I am your host, Dr. Deb.And today, I have the pleasure of meeting with Dr. James Greenblatt. I’ve known Dr. Greenblatt for a very long time. We, started lecturing together, gosh, over 15 years ago.And he is an amazing practitioner. Dr. Greenblatt is dual board certified in psychiatry and internationally recognized.as a pioneer in functional and integrative psychiatry. He’s widely regarded as the leading expert on the clinical application of low-dose lithium for mental health.Dr. Greenblatt has spent more than 30 years advancing precision medicine-based approaches that move beyond symptom management to address the root causes of mental illness.And after earning his medical degree at George Washington University.Dr. Greenblatt completed his psychiatry and residency there as a fellow in child and adolescent psychiatry.Joined John Hopkins Medical School, and he currently serves as an assistant clinical professor of Psychiatry at Tufts University. He is a prolific author. Dr. Greenblatt has written 9 books, including his newest book, Finally Hopeful. in… available in January of 2026. We can ask him about this today.And his bestsellers finally focused the breathwork, natural treatment plan for ADHD,Answers to anorexia, Functional and Integrative Medicine for Antidepressant withdrawal, and nutritional lithium, and Untold tale of Mineral and Transforms Lives, that heals the brain.He has founded, in 2019, the Psychiatry Redefined, a leading educational platform training clinicians worldwide in functional and integrative psychiatry. He is a sought-after international speaker. Dr. Greenblatt regularly lecturesOn nutritional psychiatry and the transformative role of functional medicine.I am super excited to have him here with us today. This is going to be a pleasure. You guys are going to love this conversation that we are going to have. And I am going to pick his brain today on functional and integrative psychology and psychiatry, and combining nutrition, biochemistry, and lifestyle with mental health care.I’m really, really happy to have Dr. Greenblatt with us, so I am going to bring him on, and we are going to have this amazing conversation with my friend.Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Deb, and I have with me Dr. James Greenblatt, who I have followed for… we were just chatting about this for over 20 years.He is amazing in what he is doing, and we are going to have this conversation today about integrative psychiatry and the future of mental health. So, welcome to the show, Dr. Greenblatt. James greenblatt md 03:20Thank you, Dips, good to be with you. Dr. Deb Muth 03:22Now, you’ve been pioneering this integrative psychiatry for decades. What really inspired you to bridge nutrition and psychiatry long before it’s become mainstream? James greenblatt md 03:35You know, I developed an interest in college, you know, studying nutrition, and then I remember writing papers on orthomolecular psychiatry, high dose, vitamin B3 for schizophrenia.So, I really did not think I’d be a psychiatrist. I wanted to be a pediatrician when I went to medical school, but, just early interest in nutrition and brain function.And it’s been my career now for 30-plus years. Dr. Deb Muth 04:05Wow. Can you define what integrative psychiatry actually means, and how it’s different from traditional psychiatry for most people who wouldn’t be familiar with that term? James greenblatt md 04:17Sure, I mean, I have to add the word functional as well. I mean, I think, you know, I call myself a functional psychiatrist, but for most of my career, and every book, and everything I did, I would have to use words like functional and integrative.Medicine for mental illness. And, you know, I define integrative medicine as the… Adjunctive lifestyle, mindfulness. And diet, sleep, and exercise. Dr. Deb Muth 04:46Mmm. James greenblatt md 04:46And I kind of use the term functional for kind of a deeper root cause dive, looking at nutritional deficiencies, looking at hormones, looking at genetics. And, you know, to treat patients with mental health challenges, we need both integrative and functional medicine. Dr. Deb Muth 05:05That’s awesome. You know, in our integrative space, we often kind of joke that there’s no such thing as a Prozac deficiency, right? Can you explain to our listeners how nutrient deficiencies, gut health, or inflammation can play a role in mental illness? James greenblatt md 05:23Sure, I mean, I think the most importantBeginning of this conversation would be that, you know, 10 people with depression, there might be 10 different underlying factors. Dr. Deb Muth 05:35Yeah. James greenblatt md 05:35And we do know that there’s not an antidepressant deficiency, so we have to look deeper. And… and that’s,just different than our current psychiatry model, where it’s just symptomatic-based medicine. Everyone who’s depressed. It’s an antidepressant.And by looking at functional integrative medicine, we’re looking at B12 and vitamin D and zinc and magnesium. We’re looking at hormones, we’re looking at the gut, and we’re trying to determine what might be either causing or contributing to that person’s depression. Dr. Deb Muth 06:10Is there a particular, flavor that you see more commonly with others, like depression versus anxiety versus bipolar. Is there a particular underlying factor that you see more commonly than others? James greenblatt md 06:27Well, the short answer is no, and that’s why this work takes time, because you have to think.You know, every patient that walks in the office is different. I mean, I think the overarching umbrella is nutritional deficiencies, you know, whether… regardless of weight, regardless of diet. I mean, I have people coming in who’ve been eating…You know, these ketogenic or paleo diets, you know, perfect organic foods, and are profoundly nutritionally deficient.So I think nutritional deficiencies would be number one, and then, you know, the whole host of, you know, infections and hormone problems and inflammatory issues related to celiac disease is really common in the mental health space that’s ignored. Dr. Deb Muth 07:14Yeah. Celiac disease is really not paid attention too much, other than thinking that it’s damaging the gut. They don’t really think about all the other aspects of the body that are being affected by the gut not being able to absorb the nutrients properly and then utilize them properly. It’s really sad. James greenblatt md 07:34we find out… and there’s research to support it. That’s the tragedy. This is not something, as clinicians, that we found. We have many, many years of research showing high rates of anxiety and depression, you know, amongst those with, celiac disorder because of this chronic malnutrition, and many patients present without any GI symptoms, just mental health complaints, but nobody’s looking at celiac. Dr. Deb Muth 08:02Yeah. You know, I’m sure there’s people that are listening to us thinking, there’s no way thatEverybody who’s depressed or anxious has a nutritional deficiency. When we’re… live in a country where there’s so much abundance of food, and the obesity rates are high, and most people are very plump, how could those people be deficient in nutrients? What do you say to people who think like that? James greenblatt md 08:28Yeah, I mean, I think that, you know, we have, what’s called high caloric malnutrition, so regardless of weight, I would say the vast majority of patients with a mental health issue I would say my best guess would be 90-plus percent. Dr. Deb Muth 08:47Wow. James greenblatt md 08:47We would find nutritional deficiencies. Dr. Deb Muth 08:51And part of this, we’ve discovered, is genetics. James greenblatt md 08:56People having, kind of, genetic needs for Higher amounts of certain micronutrients. Some of it is just the kinds of foods people are eating. The kind of ultra-processed food actually strips the body of micronutrients. So, it is just so common, and many of these tests are pretty simple that your primary care doctor could do in the office. Dr. Deb Muth 09:22So, traditional labs can identify some of these nutritional deficiencies. They don’t necessarily have to invest thousands of dollars in advanced nutrient testing to find these things out. James greenblatt md 09:35Absolutely. I mean, I think, you know, oftentimes when we’re working with a patient who has failed traditional psychiatric treatment, we do need some functional, testing, but I’m quite convinced we could change the trajectory of our mental health epidemic in this country by some labs that are covered by every insurance company on the planet. Like, people think of vitamin D as, you know, building bones or immune function.It has dramatic relationships to mental health problems, demonstrated over 30 years of research. So vitamin D and B12 and folate, all simple blood tests that are covered by all health insurances. Dr. Deb Muth 10:18You know, with the change of genetics, MTHFR is so popularly known these days. It’s probably the most popular genetic mutation that people know of.And in the mental health space, it plays a significant role as well in that absorption of B12 and folate. How do you look at MTHFR mutation with inside the mental health world? James greenblatt md 10:43Well, I think it’s, It’s critical, it’s required on every patient that I see, and I’ve been, known to say it would be considered malpractice for psychiatrists not to test for the MTHFR gene. Because most of my career, I’ve spent working in inpatient psychiatric hospitals and residential. So seeing those individuals that have failed outpatient treatment, so really struggling.And one of the most common things I’ve been seeing for 30 ye

    25 min

  7. Apr 27

    Episode 262 – The Root Cause of ADHD & Autism: Beyond the Diagnosis with Dr. Anju Usman Singh

    Dr. Deb Muth 0:03What are the answers to your child’s chronic allergies, ADHD, or autism?weren’t just in another prescription, but in restoring balance to their body chemistry. Today’s guest has spent nearly two decades uncovering those answers through integrative and biomedical medicine. That’s a mouthful, isn’t it?Helping children heal when nothing else seemed to work.This is the conversation about science, compassion, and changing the future of pediatric care.Welcome back to Let’s Talk Wellness Now. The show where we uncover the root causes of chronic illness, explore regenerative breakthroughs, and empower you with the practical tools to heal. I’m your host, Dr. Deb, your medical detective, and today’s episode is one every patient should hear.My guest is Dr. Anu Usman Singh, Medical Director of True Health Medical Center in Naperville, Illinois, and the owner of Pure Compounding Pharmacy.And for over 17 years, she has been pioneering evidence-based integrative interventions for children with ADD, autism, allergies, and complex gastrointestinal and metabolic disorders. She’s not only a practicing physician, she’s a researcher who’s investigated copper-zinc imbalances.metallonine dysfunction, biofilm-related infections, vitamin D in pregnancy, and hyperbaric oxygen therapy.Dr. Usman serves on the executive board of TACA, and is a faculty member at MAPS, training other practitioners in pediatric integrative care. So get ready for a conversation that will open your mind and heart to the possibilities of when medicine truly becomes holistic.If you guys can insert the ad in here, that’d be great.Well, welcome back. I’m so excited to have Dr. Usman with me today. I have known her for, oh my gosh, 15, 17 years, something like that. We’re aging ourselves. Anju 02:32Oh, yeah, when we were in our 20s, right? Dr. Deb Muth 02:35Yes, exactly. So, welcome back, and I am so excited for you to be here, because you have literally helped thousands of families over the years.But I’d love for you to share a little bit about your journey, kind of who you are, what drew you into exploring integrative and biomedical approaches for helping children and families. Anju 02:58I think my journey is similar to a lot of you out there, the audience. I mean, we’re looking to help our families, and our kids, and ourselves, and I was doing my residency at Cook County Hospital, downtown Chicago, in the 80s.And I thought, oh my goodness, if I could take care of the sickest patients, then I can take care of anybody. So I came from Indiana, and I went to Cook County, and my children, my eldest daughter, started having, severe allergies and asthma, really, really at a young age.And I went to, like, my residence, and I went to my attendings, and I said, this baby is wheezing. And they told me, babies don’t have asthma.And I said, she has all the symptoms of asthma. She has asthma. And I remember with, in her crib, I would just nebulize her, you know, and I was like, what is going on?And I figured out that she had a lot of food allergies, and I was nursing her, eating the foods that she was allergic to, and back then, in the 80s, you know, we didn’t have the internet, we didn’t have Whole Foods, and I just…being a doctor, and I didn’t even know what to do, and I felt so hopeless. And I thought, gosh, you know, I’m a doctor, I have these, like, skills, I have… people I can talk to, and I still feel so… it’s so difficult. And then this… my particular daughter, the oldest one, her name is Priya, and she developed severe, asthma, and I couldn’t figure it out. She was in junior high. Every time she would walk into the lunchroom, she would have a severe asthma attack.And I’ll be like, what’s going on? What’s going on? I kept her home over the weekend, she was better. I sent her back to school, she was bad again.And we figured it out that it was other people eating peanuts. Dr. Deb Muth 04:54Severe peanut allergy. Anju 04:56And I went to the school, and I said, she…can you, like, put her somewhere else? Can… they said, oh, no, that’s not fair to other kids and their food. And this was in the 90s. Dr. Deb Muth 05:10Yeah. Anju 05:10And so, I just…You know, my heart goes out to families who are struggling to find answers for their kids, and my daughter Priya, the one I told you about, she ended up passing away from a peanut allergy.And so, I’ve just… Dr. Deb Muth 05:26Yeah. Anju 05:27My heart goes out to parents and my own kids and their illnesses.And so I just started working with families, with kids, andIt just kind of grew from there. Dr. Deb Muth 05:40Yeah. Yeah. Yeah, and I think being a mom who went through that yourself, and…was seen but not heard, and turned away from the traditional medical community, you’re forced to start finding answers on your own. And we always feel like we’re on an island by ourselves in the medical world when we’re doing that. Anju 06:01Yeah, I, it was really hard when I found out, you know, about…Integrative medicine, and just different…ideas and approaches to diet and supplements, I thought, how come I wasn’t trained in any of this?And… Dr. Deb Muth 06:21So angry when I learned some of the things that I learned in the beginning. I was like, same thing, like, how did they not teach us this? And then I think, you know, it’s my fault, was I asleep, was I not paying attention, whatever. And then you just realize, like, there’s this whole part of the human body.That they just didn’t teach us. Anju 06:42Yeah, so then I… I, probably like you, we had to learn it on our own. There weren’t, like, classes or any way to learn this stuffAnd I just reached out. There’s a clinic that,I don’t know if you’ve heard of the Pfeiffer Treatment Center? Dr. Deb Muth 07:00No. Anju 07:01Do you know Carl Pfeiffer from the attendees.He has a clinic called the Pfeiffer Treatment Center in New Jersey. It was called the Princeton Brain Bio Center. Dr. Deb Muth 07:12And in the 70s, they did orthomolecular medicine for patients with ADD. Anju 07:18And schizophrenia. Dr. Deb Muth 07:20Mmm… Anju 07:21and depression.And they used to categorize them in 3 categories, and at the time, they called them histopenics, histidelics, and pyrolurics. Dr. Deb Muth 07:31Okay. Anju 07:32Histapenix were low histamine patients.Delix were high histamine patients, and pyrolurics were their own kind of category. We added another category of copper-zinc imbalances, and then we would categorize that population into high histamine, low histamine, pyrolurics, and copper-zinc.Now we talk about under-methylation, over-methylation. Sure. So, under-methylation is the, you know, the high histamine people, they can’t clear the histamine. And the over-methylators are, you know, what we call about low histamine now.And, and then pyrolurics and copper zinc. So…I lost my train of thought, but in the 80s, when I was going through this, in the 90s, I reached out to the Pfeiffer Treatment Center.He’s like, can I calm and just hang out and, like, see what you guys do? Because I need some answers.And I started working there and, started doing research on copper-zinc imbalances, and I did it in children with autism.And that’s how people started coming to me, and I kinda got, like. not famous, but I, you know, the word spread about, okay, we could talk about it, and Dr.Walsh was the, you know, PhD there that did a lot of the research, so we worked together for 8 years. Dr. Deb Muth 09:05Isn’t it crazy to think that we knew about histamine issues way back in the 70s? You know, I got the pleasure of being trained by, environmental medicine doctors. Dr. Wayne Konetsky and Glenn Toth taught me about environmental medicine, and what we called histamine issues that we call it today, mast cell, right? But when I was learning in the early 2000s, it was labeled as chemical sensitivity. And so it was just people that would react to everything, and we really didn’t know why, and they didn’t necessarily have this very specific allergic reaction, but we knew they were reacting, and we would try to treat them, to lower the histamine way back then. And it’s taken all these years, 25 years, to get to a point where we understand mast cell activation now, and histamine issues.And it’s really sad to me that it’s taking this long for us to identify things.And we’ve all got our journey, and I loved back in those days, too, because as I learned, I would call people up and say, hey, I just got a patient from you, and they told me this great story, and I have other people, can I come see what you were doing? And back then, everybody was very open. They were like, yes, please, come, learn. Now everybody’s like, oh, we can’t teach you, we can’t give you our secrets, but…Or pay me $20,000 to come learn with me. But back then, I mean, everybody was just… we were all in the same boat. We were all just trying to learn from each other. Anju 10:36Oh, yeah, oh yeah, and any bit of knowledge you got, you’re like… Dr. Deb Muth 10:41Yes. Anju 10:41God, you know, I learned this piece, and… Dr. Deb Muth 10:43Hmm? Anju 10:44We just kind of built from that. I keep thinking about back then, you know,the under-methylators, over-methylators, copper, zinc, and then I learned about metals.And then, as a physician, I was like, oh, okay, well, there’s mercury in vaccines, there’s aluminum in vaccines, and now I’m seeing these high levels. Dr. Deb Muth 11:04In my patients, now what happens? Anju 11:07And then we started, kind of, trying to get the word out about those things. Dr. Deb Muth 11:13Yeah. Anju 11:13And in 2000, a lot of the people that I knew put out a paper about, you know, mercury. Dr. Deb Muth 11:22And then… Anju 11:22And we all got on

    1h 3m

  8. Apr 18

    Episode 261 – Root-Cause Healing and Whole-Body Wellness

    Dr. Deb Muth 0:03What if everything you’ve been told about getting healthy is backwards?What if chasing symptoms with pills, procedures, and quick fixes is exactly why you’re still sick? Tired, inflamed, and frustrated. Today, I’m sitting down with Dr. Holly Donahue, a naturopathic doctor who walked away from corporate burnout to discover the truth.Your body already knows how to heal. You just need to remove what’s blocking it, and give it what it’s missing. If you’re done with Band-Aid solutions and ready for real, lasting transformation, this conversation changes everything. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting-edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective, and today, we’re diving into the hidden truth about whole body wellness, and why treating symptoms will never give you the vibrant health you deserve. I’m joined by Dr. Holly Donahue, a licensed naturopathic doctor with over two decades of clinical experiencing Helping high performers heal from burnout, chronic fatigue, hormone imbalance, and stubborn weight issues. She’s the founder of Simple Health, and she’s here to share the science-backed approach to root cause healing that addresses your body, mind, and spirit, not just your lab values. If you or someone you love has been diagnosed with a chronic condition, or is struggling with unexplained symptoms like fatigue, brain fog, hormonal chaos, or chronic inflammation. This episode is for you. Please share it with them. So, as usual, grab your cup of coffee, tea, or whatever helps you unwind, settle in, and let’s get started on your journey to deeper healing. And we’ll be right back after a word from our sponsor. All right. So, Dr. Donahue, let’s start with the question that’s on everyone’s mind, right? How did you transition away from corporate and into the world of, naturopath… natural medicine, naturopathic medicine, root cause medicine, all the wonderful terms we’re using for this these days? Dr. Holly Donahue 02:56Yeah, first of all, thanks for having me, Dr. Debb. I so appreciate it, and that is a beautiful question, and I will share with you my health journey and why I got into this, and… how I got to do this amazing work, right? Because I always believed, for me, my higher being is God, and it walked right into me, right? Because I was pretty happy in the apparel industry. So, just as you said, I was in the apparel industry, I, my education doesn’t really matter, but double, like, marketing and textile marketing, and I was in design, and I was working in design. from LA to London to the East Coast. And 2 days after September 11th, to sum it up, I got laid off. Even though I had been pulled out of a job where my vice president of the company was like, I want you to come down here with me, and the apparel industry, you’re switching every two to three years. For those that don’t know it, that’s just how the journey works, and I was known as a changemaker in the field. And so, here we are two days after September 11th, and I was seeing a naturopath, and I was, let’s see, 29 to 30, right? And so, prior to that, the reason why I searched out for a naturopath was because in my teenage years, and… Up until that time, I was suffering with horrible menstrual cramps and horrible depression, hence why I moved to LA, thinking if I was in the sun all the time, my life would change, which we all do, change our place, change our time, things will change. Had nothing to do with family or roots, but I thought, if I’m around sunshine all the time, I won’t be depressed. Well, wherever you go, there you are, because it went with me, right? So I had my foot down to the ground, and I was just like, I am committed to not living life like this, right? Even at 7 years old, I had strep ear all the time, and my mom’s like, we’re gonna have your tonsils out, and I’m like, no we’re not. And she goes, no, you’re gonna feel so much better, no more strep ear. And I’m like, God gave them to me for a reason, you’re not taking them out. She’s like, okay, like, I was really strong. And so, let’s wind up to 2 days after September 11th. Prior to that, I had started to retake chemistry and biology, because I haven’t taken it since my textile years, which was a different chemistry, right? And so, I thought, well, I’ll just start and see where it goes, because my naturopath at the time. Dr. Dadama was like, we need more naturopaths, and I’m like, I’m really good where I am. I love what I do, I love corporate America, I love designing, I love product development. And he’s like, no, no, no, so he kept talking. Well, when this all fell… And 2 days after September 11th, I raised my hand and I said, God, I hear you. I went off to naturopathic medicine school in my 30s. And I never looked back, and I just really believe the gift of healing was, put together for me in so many ways. And so, why do I love talking about natural medicine, naturopathic medicine? Because I was not gonna just take an antidepressant, which is what the medical world… they wanted to give me a pill for a nail, that’s what I call it. I didn’t need to be on birth control. I wasn’t sexually active. Right? So none of that made sense to me. And it wasn’t until I really changed my nutrition, began to understand who I am as a person, and what my body really needed, did I heal. Dr. Deb Muth 06:20Isn’t that amazing? Like, I think so many of us enter into the alternative quote-unquote world. Because what is happening over here in what is known as the traditional medicine world isn’t working for people, and no one’s listening to them, and we just follow the traditional protocol, whether it makes sense or not, this is the protocol, everybody gets it. There’s no individuality, no personalization, nothing that happens in that world. And so, people tend to go looking for that… that uniqueness that natural medicine and naturopaths allow to happen. And that’s where true healing actually begins, for so many people. Dr. Holly Donahue 07:02 Yes, and honestly, once my hormones were healed, hence why I talk about hormones all the time, and my thyroid was healed, and I was eating the right nutrition, and for those of you that are listening, please stop playing with nutrition, like, get on that… get on that connection of what works for you. And I’ll be honest, like, none of us as doctors can… we can guide you. what’s really good in eating, but figuring it out for yourself is important. And the other naturopath that I saw. Never healed me. I only got so far by just taking supplements and herbs. And I speak that into that, that’s why I’m so driven around the foundation of our medicine. I am not just saying this, is your nutrition. And until I changed my nutrition, and I figured out what workouts work best for me, and I took all the toxicity and mucus out of my body, I was just inflamed, and I didn’t really it. I was eating all the wrong foods. Right? My body can’t do searches and simple sugars, hence why I talk about it, and so many people are addicted to sugar, and they deny it. Dr. Deb Muth 08:11Yeah. Dr. Holly Donahue 08:11It’s a comfort food, right? So, I always say, I can’t heal you until I fix your nutrition and your sugar, and if that’s not something that you’re willing to work on with me with love, I am not the right practitioner. Because I remember it didn’t heal me. Dr. Deb Muth 08:29Yeah. I think we forget that nutrition is our medicine, right? Food is thy medicine. And it’s so easy for us to just say, but it’s easier to just take 10 supplements than it is to change my diet, cook for the whole family, and then cook for me. Nutrition is really, really difficult for people, because so much of who we are is born into nutrition, right? All of those family traditions of what we make at Christmas, or Easter, or what do you do for a celebration, when all of that changes, you kind of… you have a loss for things. So how do you work around that with people? Dr. Holly Donahue 09:12Yeah, so I look at that as, I’m always suggesting to individuals in all these different celebrations, like, if you’re the one, kind of. that is the pinnacle that’s creating the celebrations, could you change that, right? So maybe you always have people over for your children’s birthday parties, and you have cake, and, you know, you have a spaghetti dinner, whatever it looks like. I’m not judging, I’m not here to judge, I just know what works, right? Then maybe you get to change that. How about doing an outdoor activity with the children? Maybe choosing to go on a hike to the beach where they’re active. And then, you know, you do a healthy treat with them, or do we always have to have these celebrations around sugar? And I’m talking America, because I never saw this when I lived in Europe, like, the way it is here, right? Or, as adults, we’re celebrating with alcohol all the time, right? I removed sugar and alcohol from my diet years ago just because I knew I just didn’t feel good with it. I’m not judging that that’s what you need to do. So, back to your question, the other suggestion I say, if you can with your family, because I know there’s all sorts of… Hidden rules, quiet rules, ways you have to do things to be fit in. First of all, stand up for your own health, so I suggest that. And secondly, how about if you bring something to that meal that you can share with everybody that you know that you can eat? If that doesn’t work, I’m pretty sure, I’m pretty confident, unless I’m really not connected, and I’ve never had anybody not be able to maneuver this. When you go to a meal, look at where… what the protein is there, look at what vegetab

    47 min
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