Heart Rate Variability Podcast

Optimal HRV

Welcome to the Heart Rate Variability Podcast where we discuss the research and applications of heart rate variability.

  1. 5D AGO

    This Week In HRV - Episode 20

    This Week in HRV  In this episode of This Week in HRV, Matt Bennett explores five recent studies that deepen our understanding of heart rate variability across time, technology, cardiovascular health, brain aging, and addiction recovery. Together, these papers highlight both the strengths and limitations of HRV as a window into nervous system regulation. 1. Unveiling the Extremely Low Frequency Component of Heart Rate Variability Authors: Krzysztof, Adam G. Journal: Applied Sciences This study demonstrates that ultra-low-frequency HRV is not a single physiological process, but can be decomposed into two independent components reflecting circadian and ultradian rhythms. The findings expand our understanding of long-term autonomic regulation and biological timing. https://www.mdpi.com/2076-3417/16/1/426 2. Limited Evidence for Heart Rate Variability as a Predictor of Cognitive and Pathophysiological Brain Markers Authors: Sofia, Jaime D., Arie, Balewgizie, Harriëtte, Rozemarijn, Rudi, Ronald, Peter Paul Journal: Journal of Alzheimer’s Disease Using a long-term longitudinal design, this study examined whether midlife HRV predicts later cognitive performance, brain imaging findings, or Alzheimer’s biomarkers. Results suggest HRV alone is not a reliable early predictor of neurodegenerative pathology. https://journals.sagepub.com/doi/10.1177/13872877251409343 3. Beyond Motion Artifacts: Optimizing PPG Preprocessing for Accurate Pulse Rate Variability Estimation Authors: Yuna, Natasha, Aarti, Varun, Matthew S. Conference Proceedings: ACM (UbiComp) This engineering study shows that preprocessing choices—particularly band-pass filtering—strongly influence the accuracy of pulse-rate variability derived from wearable PPG sensors. The authors demonstrate that adaptive preprocessing significantly improves HRV estimation accuracy. https://dl.acm.org/doi/epdf/10.1145/3714394.3756241 4. Association of Diurnal Blood Pressure Patterns with Heart Rate Variability and Retinopathy in Patients with Essential Hypertension Authors: Fengping, Hui, Tianfeng, Chen Journal: Scientific Reports This clinical study links abnormal nighttime blood pressure patterns with reduced HRV and a markedly higher prevalence of hypertensive retinopathy. The findings highlight the relationship between circadian autonomic regulation and microvascular health. https://www.nature.com/articles/s41598-025-29694-9 5. Yoga for Opioid Withdrawal and Autonomic Regulation: A Randomized Clinical Trial Authors: Suddala, Hemant, Bharath, Jayant, Ravindra P., Nishitha, Venkata Lakshmi, Urvakhsh Meherwan, Shivarama, Ganesan, Prabhat, Bangalore Nanjundiah, Kevin P., Matcheri, Pratima Journal: JAMA Psychiatry This randomized clinical trial shows that adding yoga to standard opioid detoxification significantly accelerates withdrawal recovery, improves HRV, reduces anxiety, improves sleep, and decreases pain—demonstrating the role of autonomic regulation in addiction recovery. https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2843424 Sponsor...

    15 min
  2. JAN 6

    This Week In HRV - Episode 19

    Episode Show Notes: This Week in HRV – January 2026 Welcome to the first episode of 2026! Today, host Matt Bennett explores ten groundbreaking studies that bridge the gap between autonomic health, mental well-being, and physical performance. From the cardiac strain of early psychosis to the "neuroimmune triad" in diabetes, we dive deep into the latest science of Heart Rate Variability. Detailed Study Summaries 1. Myocardial deformation and pro-arrhythmic indices in first-episode patients with psychosis before and one year after the initiation of antipsychotic treatment Authors: Marios Plakoutsis, Aris Bechlioulis, Aidonis Rammos, Spyridon Sioros, Andreas Karampas, Georgios Georgiou, Lampros K. Michalis, Katerina K. Naka, and Petros Petrikis. This study highlights that a first psychotic episode is a full-body stressor causing immediate autonomic imbalance. Even without prior heart disease, patients showed abnormal HRV and subtle weakening of heart muscle contraction. While treatment rebalances the autonomic system, it requires vigilant monitoring due to medication-induced QT interval prolongation. 2. Perception of effort decreases with motor sequence learning Authors: Bahram Ghafari Goushe, Thomas Mangin, Benjamin Pageaux, and Jason L. Neva. Learning a new skill isn't just a brain-based phenomenon. This experiment shows that as a task becomes automated, the body stays calmer (higher RMSSD) and the subjective perception of effort drops, reducing the physiological "price" of performance. 3. Serum cytokine levels and heart rate variability in the frequency domain in patients with chronic Chagas heart disease Authors: Reinaldo B. Bestetti Sr., Renata Dellalibera-Joviliano, Milton Faria Junior, Rosemary A. Furlan Daniel, and Cláudia C. Domingos. Focusing on the inflammatory reflex, researchers found that Interleukin-23 (IL-23) specifically correlates with reduced vagal tone in Chagas heart disease, suggesting this cytokine interferes with the nervous system's ability to regulate the heart. 4. Research on changes in psychological, physical fatigue and emotional states in the National Youth Orienteering Preparation Camp Authors: Haiyan Li. Comparing athletes at an intensive camp to those training at home, this study proves that structured recovery (fixed hydration, rest, and mental skills training) leads to significantly better HRV adaptations and lower cortisol, preventing burnout despite high training loads. 5. Autonomic-inflammatory crosstalk in diabetic atherogenesis: a neuroimmune triad (HRV-LMR-hsCRP) predicts carotid plaque risk in type 2 diabetes Authors: Xinrui Zhou, Xiaowei Bai, Li Ding, Shuai Zhang, and Ya Li. This paper introduces a practical "neuroimmune triad"—combining HRV with immune markers (LMR and hsCRP)—to accurately predict the risk of carotid plaques in diabetic patients, identifying those at highest risk for stroke. 6. Effect of Tai Chi and Qigong on Heart Rate Variability: A Systematic Review and Meta-Analysis Examining Baseline Autonomic Function and Intervention Complexity as Moderators in Adults Authors: Yasmine A. Gunawan, Mein-Woei Suen, Hanifa M. Denny, Ishita Chauhan, Milcha Fakhria, Siswi Jayanti, and Earl F.I. Mallari. A meta-analysis of 15 studies confirms that mind-body exercises improve HRV regardless of routine complexity. However, gains are largest for those who enter the practice with a relatively healthy baseline autonomic state. 7. Sympathovagal imbalance in drug-naïve chronic obstructive pulmonary disease patients: a physiological mechanism to cope with the severity of airway obstruction in an observational study Authors: Durgesh K. Gupta, Shibu S. Awasthi, Suman Gupta, and Himani H. More. In COPD, the body reflexively boosts sympathetic drive t...

    24 min
  3. 12/30/2025

    The 2024 Year in Review — Research That Shaped 2025

    The 2024 Year in Review — Research That Shaped 2025 The Heart Rate Variability Podcast In this special "Year in Review with a Twist," we shift our focus from the weekly news cycle to the big picture. We examine the most influential, highly cited research of 2024 to understand how these findings are revolutionizing clinical thinking and personal wellness in 2025. HRV is no longer just a metric on a wearable; it has become the definitive framework for understanding resilience, adaptation, and human regulation. Episode Highlights The Anxiety Biomarker: Why 2024 research confirms HRV as a "top-down" signal of how the brain calms itself and its potential for identifying anxiety subtypes. Combatting "Inflammaging": Exploring the link between vagal tone and chronic low-grade inflammation in aging populations. The Autonomic Conditioning of Exercise: How physical activity trains the nervous system, not just the heart muscle. Context is King: A deep dive into the 2024 "Sensitivity Review" highlighting how noise, heat, and even genetics must be accounted for in accurate readings. Biofeedback Frontiers: From COPD and Spinal Cord Injury to classroom attention, we look at how HRV training is breaking new ground in rehabilitation and education. Key Research Reviewed Psychophysiology & Mental Health (2024): A landmark review synthesizing decades of data to establish HRV as a marker of prefrontal cortex regulation over the amygdala in anxiety disorders. Gerontology & Immunology (2024): Research into "Inflammaging," positioning HRV as a non-invasive biomarker for biological age rather than just chronological age. Sports Science & Performance (2024): A systematic review on HRV-guided training, emphasizing individual baselines over population norms for sustainable athletic performance. Clinical Biofeedback Trials (2024): Notable studies involving COPD patients and those with chronic spinal cord injuries, proving the feasibility of HRV training even in complex physiological cases. Neurodevelopmental Interventions (2024): Exploratory research into using HRV biofeedback for anxiety in Autism Spectrum Disorder and attention-building in school-aged children. The 2025 Takeaway "The question is no longer whether HRV is relevant, but how we apply it thoughtfully and responsibly. Autonomic flexibility is the foundation of emotional resilience, physical health, and cognitive performance." Sponsor This episode is brought to you by Optimal HRV. Bridge the gap between data and action with evidence-based tools designed for individuals, clinicians, and organizations. Explore our professional dashboards and HRV training e-gift cards today. Learn more at www.optimalhrv.com Disclaimer: The information shared in this podcast is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before changing your health or wellness routines.

    10 min
  4. 12/23/2025

    This Week In HRV Edition - Episode 17

    This Week in Heart Rate Variability: Air Pollution, Spiritual Wellbeing, Consciousness & Clinical Prediction In this episode of The Heart Rate Variability Podcast – This Week in HRV, we expand the horizons of autonomic science. From the hidden impact of environmental pollutants to the neuro-spiritual connection of the "heart-brain axis," we examine how HRV serves as a vital bridge between our environment, our consciousness, and our clinical outcomes. Episode Highlights Environmental Stressors: New research into how air pollution and lead exposure synergistically drive autonomic dysfunction. The Spirituality-HRV Link: Exploring Bayesian modeling of Heartbeat Evoked Potentials (HEP) as a biomarker for mental and spiritual wellbeing. HRV as a Clinical Life-Line: A deep dive into a major meta-analysis confirming HRV’s power to predict mortality in heart failure patients. Mapping Consciousness: How 24-hour HRV monitoring is helping clinicians differentiate between unresponsive wakefulness and recovery in patients with disorders of consciousness. Precision and Reliability: Critical insights into the reliability of short-term HRV measurements across different body positions and environments. Featured Studies & Resources Environmental Research (2025) — Air Pollution & Chronic Lead Exposure: The synergistic impact of environmental toxins on cardiac autonomic function. Link to Study Cogent Psychology (2025) — Bayesian Modeling of HEP and HRV: An exploratory study on using HRV and heart-brain communication as biomarkers for spiritual health. Link to ResearchGate Scientific Reports (2025) — The Multidimensional Perspective of HRV: A comprehensive look at the brain-heart axis (BHA) and its role in predicting multi-system disease. Link to Nature Cureus (2025) — HRV as a Predictor of Mortality in Heart Failure: A systematic review and meta-analysis on the prognostic value of HRV in cardiovascular care. Link to Cureus Scientific Reports (2025) — Clinical Reliability of Short-Term HRV Insights into the consistency of HRV measurements in dual-environment and dual-position settings. Link to Nature Acta Neurologica Belgica (2025) — HRV in Disorders of Consciousness Using 24-hour HRV metrics to identify emergence from minimally conscious states (PMID: 41389121). Link to PubMed Psicothema (2025) — Autonomic Modulation & Psychological States Examining the latest protocols for integrating HRV into psychological and behavioral health assessments. Link to ScienceDirect Key Takeaway The "Heart-Brain Axis" is more than a concept—it is a measurable r...

    36 min
  5. 12/16/2025

    This Week In HRV Edition - Episode 16

    This Week in Heart Rate Variability: Metabolic Syndrome, Nerve Blocks, EDS & Autonomic Health In this episode of The Heart Rate Variability Podcast – This Week in HRV, we explore how the autonomic nervous system function connects metabolic disease, genetic disorders, targeted neural interventions, and the future of biofeedback science. Episode Highlights How Metabolic Syndrome drives chronic sympathetic overactivation and reduced HRV Experimental evidence showing how the stellate ganglion block directly alters HRV and sympathetic tone New data validating dysautonomia in Ehlers–Danlos Syndrome using HRV and autonomic testing Why HRV is emerging as a critical clinical and research biomarker A preview of the 2026 AAPB Annual Scientific Meeting and why it matters for clinicians and researchers Featured Studies & Resources Cureus (2025) — Autonomic Nervous System Dysregulation in Metabolic Syndrome https://www.cureus.com/articles/431819-autonomic-nervous-system-dysregulation-in-metabolic-syndrome-an-association-with-hypertension-and-cardiovascular-risk#!/ Autonomic Neuroscience (2025) — Selective Sympathetic Action on HRV After Stellate Ganglion Block https://www.sciencedirect.com/science/article/abs/pii/S1566070225001298 Cureus (2025) — Heart Rate Variability and Intrinsic Autonomic Coupling in Ehlers–Danlos Syndrome https://www.cureus.com/articles/429326-heart-rate-variability-and-intrinsic-autonomic-coupling-in-ehlers-danlos-syndrome?score_article=true#!/ Association for Applied Psychophysiology and Biofeedback (AAPB) About AAPB: https://aapb.org/about 2026 Annual Conference: https://aapb.starchapter.com/meetinginfo.php?id=43&ts=1763415344 Key Takeaway Heart rate variability is a universal marker of resilience, translating metabolic stress, genetic vulnerability, and neural interventions into measurable physiological signals. HRV is no longer just a wellness metric—it's a clinical and scientific lens into autonomic health. Sponsor This episode is sponsored by Optimal HRV, providing evidence-based tools for measuring and training heart rate variability for individuals, clinicians, and organizations. Now offering e-gift cards for HRV training, app access, and professional dashboards. Learn more at www.optimalhrv.com

    17 min
  6. 12/09/2025

    This Week In HRV Edition - Episode 15

    Episode 15 – This Week in Heart Rate Variability Welcome to this week's exploration of the latest HRV science. In Episode 15, we discuss nine newly published studies that expand our understanding of HRV in mental health, physiology, chronic illness, and digital health innovation. This episode highlights remote biofeedback, pediatric heart dynamics, pregnancy and thyroid status, elite performance, cardiac rehabilitation, personalized training prediction, global research trends, autoimmune flare detection, and neurostimulation safety. Featured Studies: Remote HRV Biofeedback and Mental Health “Efficacy and Methodology of Remote Heart Rate Variability Biofeedback Interventions for Mental Health: A Systematic Review and Meta-Analysis” Vann-Adibe et al., Applied Psychophysiology and Biofeedback (2025) https://link.springer.com/article/10.1007/s10484-025-09750-w Pediatric HRV and Cardiac Complexity “Age-dependent patterns of cardiac complexity unveiled by topological data analysis of pediatric heart rate variability” Domínguez-Monterroza et al., PLOS ONE (2025) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337620 Subclinical Hypothyroidism in Pregnancy and HRV “Comparative Evaluation of Thyroid Profiles and Heart Rate Variability in Newly Diagnosed Subclinical Hypothyroid and Euthyroid Pregnant Women” Singh et al., Cureus (2025) https://www.cureus.com/articles/427419-comparative-evaluation-of-thyroid-profiles-and-heart-rate-variability-in-newly-diagnosed-subclinical-hypothyroid-and-euthyroid-pregnant-women?score_article=true#!/ Performance Optimization in Firefighters “Mental imagery and breathing exercises integrated into a standardized warm-up routine enhance sympathetic activation and optimize muscular performance in firefighters” Biéchy et al., PLOS ONE (2025) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337431 Innovative Respiratory-Synchronized Pacemaker University of Auckland research feature: “Pacemaker could help the heart heal” Paton, Ben-Tal, Nogaret, and Stiles https://www.auckland.ac.nz/en/news/2025/12/02/pacemaker-could-help-heart-heal.html HRV and Personalized Fitness Modeling “Advancing training effectiveness prediction in mass sport through longitudinal data: A mathematical model approach based on the Fitness-Fatigue Model” Wang et al., PLOS ONE (2025) https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0337824 Global Trends in HRV Research “A Two-Decade Bibliometric Analysis of Heart Rate Variability Research (2005–2024)” Sharma et al., Psychiatry Research (2025)

    34 min
3.5
out of 5
10 Ratings

About

Welcome to the Heart Rate Variability Podcast where we discuss the research and applications of heart rate variability.

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