LifeLONG with Ethan Suplee

2WAY

The premise is simple and serious: health isn’t a finish line; it’s an ongoing practice. And every Monday at 7PM ET, the show will offer a place to reset, recalibrate, and recommit. Ethan brings to this project what so few people in the “wellness” world do: lived experience, humility, humor, and a refusal to peddle shortcuts. LifeLONG will nurture honest conversations like no other about what it takes to build and maintain a healthier life. Each episode will blend real talk, audience participation, and practical tools: food, fitness, mindset, recovery, and community. Viewers can ask questions, share their own challenges, and shape the discussion in real time. The goal is not perfection, but progress. Not performance, but connection. LifeLONG also reflects the larger mission of 2WAY: to create thoughtful, substantive live programming that brings people together around ideas, challenges, and the hard work of self-improvement — all in real time, without a script. If you’re beginning a health journey, returning to one, or simply looking for a weekly moment of accountability, I hope you’ll join us for this first step. Hosted on Acast. See acast.com/privacy for more information.

  1. What Actually Makes Fitness Stick Long-Term? | LifeLONG Ethan Suplee

    FEB 24

    What Actually Makes Fitness Stick Long-Term? | LifeLONG Ethan Suplee

    Today on LifeLONG, Ethan sits down with Dr. Joey Muñoz, Ph.D., nutrition scientist, coach, and founder of Fit4Life Academy. https://fit4lifeacademy.health/ Dr. Muñoz earned his Ph.D. in Nutrition Sciences from Florida State University and has spent more than a decade helping everyday people improve their health and transform their physiques using evidence-based strategies, not fads or fitness folklore. We talk about what actually works when it comes to fat loss, muscle gain, metabolism, and sustainable habits. No gimmicks. No miracle protocols. Just science you can use in real life. If you’re tired of conflicting advice and want clear, practical guidance grounded in research, this one’s for you. Topics include: • Nutrition myths that refuse to die • Fat loss vs. metabolic health • How to build muscle without overcomplicating it • Habits that actually stick • What the science really says about dieting GET A FREE COPY of Dr Joey's eBook here (00:00) Show Introduction & Blizzard Cooking (01:45) Guest Introduction (04:40) Health vs. Weight Loss & Childhood Diets (10:19) The Power of Education in Fitness (13:20) The Mental Toll of Weight Loss (19:45) The Secrets of Weight Loss Maintenance (25:11) Audience Q&A: Transitioning to Maintenance (46:00) Audience Q&A: The "David Goggins" Mindset (53:35) Rapid Fire Questions (58:45) Wrap-Up & Free E-book (01:00:20) The Daily Nudge & Sign-Off Want to be on a future episode? Register here to join the conversation: 2way.tv/ethansuplee Don't forget to subscribe to the YouTube for clips, full episodes, and more! If you have any inspirational quotes to share, post them to Ethan's subreddit, r/EthanSupleeLifeLONG. It’s also a great place to discuss episodes, post about your successes, and embrace the community. Lastly, you can send video questions to ethansupleeshow@2way.tv and we will play them on the show.  Hosted on Acast. See acast.com/privacy for more information.

    1h 1m
  2. No Filters AMA: Presidents Day with Ethan Suplee and Lisa De Pasquale | LifeLONG Ethan Suplee

    FEB 24

    No Filters AMA: Presidents Day with Ethan Suplee and Lisa De Pasquale | LifeLONG Ethan Suplee

    Welcome to a special Presidents Day we pre-recorded an AMA with a viewer mailbag. Plus Lisa De Pasquale, author of The Gen X Handbook for Middle Age: The Pursuit of Health, Success, and Human Fulfillment, will be joining us later to keep me honest. 📘 Grab Lisa’s book: https://www.simonandschuster.com/book... 🐦 Follow on X/Twitter: @LisaDeP 📸 Follow on Instagram: @Lisa_DeP This episode also features an all-doctors lineup of clips with Dr. Casey Means, Dr. Jason Fung, Dr. Ben Bikman, and Dr. Mike Israetel. Lots of good fuel for health, metabolism, and big-picture life questions. (00:00) Show Introduction & AMA Format (01:52) Q&A: Correcting Calories After Indulging (03:36) Q&A: Three Movies to Rebuild Humanity (05:10) Q&A: The Internal vs. External Transformation (11:17) Q&A: Best Cultural Dishes for Weight Loss (13:15) Q&A: Hacks for Dealing with Hunger Pains (17:15) Q&A: Best Food for Every Meal & Guest Lisa De Pasquale (23:41) Dexa Scans, Body Recomposition, & Creatine Jello (28:36) Lisa's Book: The Gen X Handbook for Middle Age (32:54) Video Reaction: Dr. Casey Means on Walking (36:48) Video Reaction: Dr. Ben Bikman on Insulin & Breakfast (47:02) Video Reaction: Dr. Jason Fung on the Power of Community (50:40) Video Reaction: Dr. Mike Israetel on Resistance Training as We Age (56:08) Wrap-Up, Michael Jordan Quote, & Sign-Off Want to be on a future episode? Register here to join the conversation: 2way.tv/ethansuplee Don't forget to subscribe to the YouTube for clips, full episodes, and more! If you have any inspirational quotes to share, post them to Ethan's subreddit, r/EthanSupleeLifeLONG. It’s also a great place to discuss episodes, post about your successes, and embrace the community. Lastly, you can send video questions to ethansupleeshow@2way.tv and we will play them on the show.  Hosted on Acast. See acast.com/privacy for more information.

    58 min
  3. GLP-1s on Trial! Ozempic, Metabolic Health & What You Really Should Know | LifeLONG

    FEB 11

    GLP-1s on Trial! Ozempic, Metabolic Health & What You Really Should Know | LifeLONG

    Want to join the show live and just hang out with Ethan and Co.? Zoom isn’t just Q&A. It’s your all-access pass to LifeLONG: see some pre-show prep, stick around after we stop recording, and connect with the crew and other viewers. Get your personalized link here: 👉 https://us06web.zoom.us/meeting/register/jrw2LEWiSwy2fXG9ytocNA Dave Knapp, founder of On The Pen, joins Ethan Suplee on LifeLONG for a wide-ranging conversation about the latest developments in GLP-1 medications, metabolic health, Type 2 diabetes, and obesity treatment. https://www.onthepen.com/about Knapp has become one of the most trusted independent voices covering this fast-moving space, blending research, patient experience, and straight-talk analysis to help people understand how drugs like Ozempic, Wegovy, and Mounjaro actually work. From the surprising origin story of GLP-1 in Gila monster venom to today’s blockbuster prescriptions and new therapies on the horizon, we break down what’s real, what’s hype, and what these medications mean for long-term health. Timing felt right. It’s the Monday after the Super Bowl. The snacks are gone, the leftovers are questionable, and half the country is quietly promising to “get it together.” Perfect moment to talk metabolism, habits, and what sustainable change actually looks like. We cover the newest GLP-1 headlines, how these drugs affect appetite and blood sugar, common misconceptions, and how to think about obesity as a chronic, relapsing condition rather than a willpower problem. Watch live on YouTube — or register above to come backstage, participate, and ask questions in real time. Subscribe for more conversations on strength, longevity, and lifelong health. (00:00) Intro: The Super Bowl Hangover  (00:45) Novo Nordisk Sues Hims: The First Patent Lawsuit  (05:03) Did Hims Want This Fight? FDA Defiance  (09:27) The Marketing Problem: Being "First to Market"  (13:00) "Project Trump," Price Wars, and the FDA Crackdown  (17:05) The Science: Why Compounding Pills is Risky  (20:57) The Debate: Pharma R&D Costs vs. Patient Access  (26:08) Super Bowl Ads: Serena Williams & Obesity Stigma  (31:02) Why Insurance Companies Deny Coverage  (37:50) Q&A: Integrating Mental Health with GLP-1s  (42:36) Q&A: What If the Meds Don't Work? (Non-Responders) (46:49) Q&A: Managing Stress & Diabetes (Trulicity to Mounjaro)  (49:55) Q&A: De-Moralizing Meds—They Are Just Tools  (56:08) Lightning Round with Dave Knapp  (58:38) Daily Nudge: Bad Bunny & Outro Want to be on a future episode? Register here to join the conversation: 2way.tv/ethansuplee Don't forget to subscribe to the YouTube for clips, full episodes, and more! If you have any inspirational quotes to share, post them to Ethan's subreddit, r/EthanSupleeLifeLONG. It’s also a great place to discuss episodes, post about your successes, and embrace the community. Lastly, you can send video questions to ethansupleeshow@2way.tv and we will play them on the show.  Hosted on Acast. See acast.com/privacy for more information.

    1 hr
  4. Let's talk Weight Cycling: GLP1s, Gym Mistakes, and the new Food Pyramid | LifeLONG Ethan Suplee

    JAN 13

    Let's talk Weight Cycling: GLP1s, Gym Mistakes, and the new Food Pyramid | LifeLONG Ethan Suplee

    This episode of LifeLONG features bodybuilding coach Dylan Guynn and tackles the intersection of muscle building, sustainable fat loss, and new public health developments. Ethan opens by criticizing the 2026 US government alcohol guidelines, which removed the specific numerical limits of one drink per day for women and two for men. The new guidance vaguely suggests drinking less if you can, a change Ethan argues benefits corporate lobbyists while obscuring the link between alcohol and cancer. The conversation then shifts to body composition, with Dylan explaining how a bodybuilding lifestyle, focused on muscle sparing rather than just weight loss, creates a more sustainable long-term health model compared to the extreme peaks and valleys of crash dieting. A significant portion of the discussion focuses on GLP-1 agonists like Ozempic and Wegovy. Dylan and Ethan explore the risks of muscle wasting on these medications due to low caloric intake and emphasize the necessity of high protein consumption and resistance training to maintain lean tissue. They discuss the phenomenon of diet fatigue, noting that even with appetite suppression, the nervous system accumulates stress that requires management through diet breaks or fatigue reduction strategies. Ethan expresses concern about patients cycling off these drugs and regaining weight as fat, potentially leading to a worse body composition over time. They also advocate for using GLP-1s as a tool to establish healthy habits, potentially allowing for lower maintenance doses rather than complete cessation . The episode also includes a reaction to a clip from strength coach Mike Boyle, who argues against the train to failure mentality, suggesting that consistency is far more effective than high-intensity workouts that leave you crippled. Dylan agrees, noting that while training to failure can increase muscle growth, it fills the fatigue bucket too quickly for most people to sustain long-term. Finally, the show touches on the flipped food pyramid, with both hosts supporting a protein-forward approach. The episode concludes with a Daily Nudge on persistence from Ralph Waldo Emerson, reminding listeners that strength is built by returning to the work day after day. Want to be on a future episode? Register here to join the conversation: 2way.tv/ethansuplee Don't forget to subscribe to the YouTube for clips, full episodes, and more! If you have any inspirational quotes to share, post them to Ethan's subreddit, r/EthanSupleeLifeLONG. It’s also a great place to discuss episodes, post about your successes, and embrace the community. Lastly, you can send video questions to ethansupleeshow@2way.tv and we will play them on the show.  Hosted on Acast. See acast.com/privacy for more information.

    59 min
  5. Did Ozempic Kill the New Year’s Resolution? | LifeLONG Ethan Suplee

    JAN 6

    Did Ozempic Kill the New Year’s Resolution? | LifeLONG Ethan Suplee

    This week on LifeLONG, Ethan Suplee and Dr. Spencer Nadolsky investigate a strange phenomenon that hit fitness centers this January: the gyms were completely empty. We explore the conspiracy theory that the rise of GLP-1 agonists like Ozempic and Wegovy has finally killed the desperate New Year’s Resolution rush, allowing people to focus on their health year-round instead. Dr. Nadolsky breaks down the hard data behind these nuclear tools for weight loss, specifically addressing the terrifying headlines about muscle wasting. He reveals the real difference between Semaglutide, which can result in nearly 40% fat-free mass loss, and Tirzepatide (Mounjaro), which averages closer to 25%, while explaining why DEXA scans often mistake fluid loss for muscle loss. Beyond the medication, they dive deep into the psychology and physical reality of extreme weight loss. Ethan and Dr. Nadolsky debate the controversial question of whether obesity is truly a choice or a result of genetics clashing with our modern food environment, with Ethan sharing his perspective on how he didn't choose obesity but had to actively choose his recovery. Ethan also gets incredibly vulnerable about the disaster of his loose skin removal surgeries, sharing graphic details about the recovery process that most influencers won't tell you, including the mental toll of being bedridden for weeks. Finally, we discuss why 2026 might be the Year of Fiber, why Dr. Nadolsky ranks it above protein for GLP-1 users, and the specific strategies you need to build muscle while on these medications. Want to be on a future episode? Register here to join the conversation: 2way.tv/ethansuplee Don't forget to subscribe to the YouTube for clips, full episodes, and more! If you have any inspirational quotes to share, post them to Ethan's subreddit, r/EthanSupleeLifeLONG. It’s also a great place to discuss episodes, post about your successes, and embrace the community. Lastly, you can send video questions to ethansupleeshow@2way.tv and we will play them on the show.  Hosted on Acast. See acast.com/privacy for more information.

    57 min

Ratings & Reviews

5
out of 5
2 Ratings

About

The premise is simple and serious: health isn’t a finish line; it’s an ongoing practice. And every Monday at 7PM ET, the show will offer a place to reset, recalibrate, and recommit. Ethan brings to this project what so few people in the “wellness” world do: lived experience, humility, humor, and a refusal to peddle shortcuts. LifeLONG will nurture honest conversations like no other about what it takes to build and maintain a healthier life. Each episode will blend real talk, audience participation, and practical tools: food, fitness, mindset, recovery, and community. Viewers can ask questions, share their own challenges, and shape the discussion in real time. The goal is not perfection, but progress. Not performance, but connection. LifeLONG also reflects the larger mission of 2WAY: to create thoughtful, substantive live programming that brings people together around ideas, challenges, and the hard work of self-improvement — all in real time, without a script. If you’re beginning a health journey, returning to one, or simply looking for a weekly moment of accountability, I hope you’ll join us for this first step. Hosted on Acast. See acast.com/privacy for more information.

You Might Also Like