Science Friday

4.4 (6.5K)
Life Sciences
Daily

Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.

7h ago

People are microdosing GLP-1s for weight loss. Is it safe?

There’s a new trend in the world of weight loss: microdosing GLP-1 drugs. Online health clinics are promising big results with microdoses drugs like Ozempic, Wegovy, and Zepbound. Many source their drugs from compounding pharmacies, which can get complicated because compounding pharmacies are able to create different doses and formulations that haven’t gone through the FDA approval process. So, what do we know about the safety and efficacy of microdosing GLP-1s? And is there research to back up this approach? Flora talks with two experts to help sort through what we do and don’t know: pharmacist Joey Mattingly, who studies compounded GLP-1 drugs and how they’re marketed to patients, and obesity medicine physician Jorge Moreno. Guests: Dr. Joey Mattingly is a pharmacist studying compounded GLP-1 drugs, and an associate professor of pharmacotherapy at the University of Utah. Dr. Jorge Moreno is an obesity medicine physician and an assistant professor at the Yale University School of Medicine. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
1d ago

Terence Tao on how AI math solutions miss the point

In a matter of months, AI has transformed the field of mathematics. In September, OpenAI claimed that an AI model solved the million-dollar Navier-Stokes equation. Then, a few weeks later, OpenAI shared results for more than 350 previously unsolved math problems. The news has prompted an existential conversation among mathematicians: In an age of AI, what’s the role of the human mathematician? It’s a question that Terence Tao, largely considered one of the greatest mathematicians of this generation, is reckoning with right now. He speaks with Flora about how AI has upended the mathematics world, what the role of math is in this day and age, and why the real value of mathematics lies in the journey, not just the answer. Tao is also the author of the forthcoming book, “Six Math Essentials,” which tells the story of math and how it shapes our world. Guest: Dr. Terence Tao is a professor of mathematics at the University of California, Los Angeles and the author of “Six Math Essentials.” Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
2d ago

What was life like for Tyranossaurus rex?

While Tyrannasaurus rex has reached celebrity status in pop culture thanks to movies like “Jurassic Park” and famous fossils, it can be difficult to imagine what everyday life was like for this charismatic prehistoric predator. Producer Kathleen Davis speaks to science writer Riley Black, who has investigated and reimagined life of the T. rex in her new book, “Tyrant Lizard Queen.” Prepare to get a grounding new perspective on this larger-than-life monster. Read an excerpt from “Tyrant Lizard Queen: The Love, Life, and Terror of Earth’s Greatest Carnivore” Guest: Riley Black is a science writer and the author of several books, including “When the Earth Was Green,” “The Last Days of the Dinosaurs,” and “Tyrant Lizard Queen.” Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
3d ago

Isabella Rossellini on how acting connects to animal cognition

Pass the cocktail napkins and refill your glass because we’re having a dinner party. You’ll be between Isabella Rossellini, the Italian model, movie star, and director; and ecologist Carl Safina, author of many books, including “Beyond Words: What Animals Think And Feel." This might seem like an unusual pairing, but it turns out they have a surprising amount in common. Both have a deep interest in animal cognition and our place in the natural world, but bring distinctly different lenses to their exploration of this corner of science. They join Host Flora Lichtman in the studio to discuss. Guests: Isabella Rossellini is an actor and director, and runs Mama Farm in Brookhaven, New York. Dr. Carl Safina is an ecologist and the author of “Beyond Words: What Animals Think and Feel." Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
5d ago

Why are we changing the way we keep time?

The time we see on our phones and clocks is based on the Earth’s rotation. But that rotation speed varies, so if it speeds up or slows down, our time measurements get thrown off. To solve this problem, timekeeping scientists have been deploying leap seconds to keep our clocks aligned with our planet. That is, until last week. After decades of debate, a global committee of timekeepers voted to kill the leap second. Host Flora Lichtman speaks to journalist Emma Gometz, who reported on the change for Scientific American, and physicist Judah Levine, to understand why this decision is a big deal and what exactly it means for us. Guests: Emma Gometz is the associate newsletter editor at Scientific American, based in Queens, New York. Dr. Judah Levine is a faculty member in the Department of Physics and a fellow of JILA at the University of Colorado, Boulder. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
6d ago

Kazuo Ishiguro on emotional truth in sci-fi and in our AI reality

The movie “Klara and the Sun,” in theaters now, is based on the 2021 novel of the same name by Kazuo Ishiguro. The story is set in the future and is narrated by Klara, a robotic “Artificial Friend,” whose job is to be a companion to a sick teenage girl. In the 5 years since the release of the novel, the AI landscape has changed profoundly. Flora talks to novelist Kazuo Ishiguro about the rapid evolution of artificial intelligence, the intersection of art and science, and his hopes—and fears—for the future of this tech. Guest: Kazuo Ishiguro is a novelist and Nobel laureate, based in London, England. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Oct 22

Is that garbage can bear resistant? These bears will find out

Have you ever wondered what it means for something to be bear resistant? How do manufacturers know that the cooler you take camping or the compost bin in your backyard will keep hungry bears out? Wonder no more! Journalist Alex Davies’ new book “Kobuk the Destroyer: And Other Tales from the Wild, Unseen World of Test Engineering” takes you inside the workplace of the grizzly bears whose job it is to tear apart consumer goods. Davies joins Ira to discuss how bears do it, and other creative experiments to test the safety of jet engines, pill bottles and more. Read an excerpt from “Kobuk the Destroyer.” Guest: Alex Davies is a journalist and author of “Kobuk the Destroyer: And Other Tales from the Wild, Unseen World of Test Engineering.” Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Oct 21

Jennifer Doudna on what it takes to be a good scientist

In 2020, Jennifer Doudna shared the Nobel Prize in chemistry for the development of the gene-editing technique CRISPR. Along with related techniques, it has become an essential tool in genetics, allowing specific sections of genetic code to be cut and replaced in a genome. It’s an advance that has changed the game in biological research. Doudna talks with Ira Flatow about the path that led to the development of CRISPR, her own route into research, and her thoughts on the attributes needed for success in science. Guest: Dr. Jennifer Doudna is a professor of biochemistry, biophysics and structural biology at the University of California, Berkeley. She is a 2020 Nobel Laureate in chemistry, and the 2026 winner of the Priestley Medal. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Photo credit: Glenn Ramit Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that’s keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

See All (1.4K)

Ira Flatow

Host
Flora Lichtman

Host
Joey Mattingly

Guest
Jorge Moreno

Guest
Terence Tao

Guest
Isabella Rossellini

Guest
Carl Safina

Guest
Kazuo Ishiguro

Guest
Jennifer Doudna

Guest
Jason Glenn

Guest

4.4

out of 5

6,462 Ratings

Love the show

4d ago

aaaassaasaaaaaaaaa

Always entertaining and informative. Enjoy the puns. Great work!
Loss of science museums

Oct 14

Lorax Seanachie

I love this podcast. Interesting topics discussed by knowledgeable people in an intelligent way. Have you done a story about the loss of science museums? The Academy of Natural Sciences Museum in Philadelphia, the oldest natural history museum in this hemisphere, recently closed its doors. There is a large contingent of scientists, former staff, and fans of this iconic museum fighting to get it reopened and on firm ground. The Sternberg Museum of Natural History in Kansas is also being shuttered. What is going on here? I’d love to hear your views on this tragic turn of events. Thanks!
concussion episode

Oct 1

A14obx

We needed a more aggressive followup questioning when the interviewees answer to a study showing 25% of the participants will have brain injuries leading to CTE. The response was, it needs more study. How cruel! The activity should be halted immediately! Participants paying a torturous price and the family and community pick ip the bill!
Great series, but ANNOYING COMMERCIALS

Sep 30

Saurolophus

I love this series! However, there’s no way to listen without suffering insipid commercial interruptions. I’d pay for a commercial-free subscription if they offered one.

Covering the outer reaches of space to the tiniest microbes in our bodies, Science Friday is the source for entertaining and educational stories about science, technology, and other cool stuff.